louise flecher won an oscar with her performance in "one flew over..." she is a great actress.
imho, the best players in star treks were: stewart, spiner, picardo, shimerman, auberjonois, the guy who played rom, robinson, jeff combs and oh yes, jeri ryan. don't laugh, check out her performance in the episode which she becomes "the doctor"...
the worst were brooks (i liked sisko but towards the end he was overacting), visitor (fakeheat) and garret wang. wes crusher is the bottom of course.